021-51111890
购物车（）
sales@molnova.cn
9-hydroxy Stearic Acid
CAS No. 3384-24-5
9-hydroxy Stearic Acid ( —— )
产品货号. M34907 CAS No. 3384-24-5
9-Hydroxyoctadecanoic acid (9-HSA) 是一种 HDAC1 抑制剂，在 5 μM 下可抑制约 66.4% 的 HDAC1 酶活性。9-Hydroxyoctadecanoic acid 显示抗癌活性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥504 | 有现货 |
|
| 5MG | ￥1389 | 有现货 |
|
| 10MG | ￥2398 | 有现货 |
|
| 25MG | ￥3847 | 有现货 |
|
| 50MG | ￥5615 | 有现货 |
|
| 100MG | ￥7551 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称9-hydroxy Stearic Acid
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述9-Hydroxyoctadecanoic acid (9-HSA) 是一种 HDAC1 抑制剂，在 5 μM 下可抑制约 66.4% 的 HDAC1 酶活性。9-Hydroxyoctadecanoic acid 显示抗癌活性。
-
产品描述9-Hydroxyoctadecanoic acid (9-HSA) is an HDAC1 inhibitor that inhibits ～66.4% HDAC1 enzymatic activity at 5 μM. 9-Hydroxyoctadecanoic acid shows anticancer activity.
-
体外实验Cell Line:HT29 cell Concentration:100 μM Incubation Time:24 h Result:Decreased S-phase activity by 50.2% compared with untreated controls, and the growth inhibition was associated with a strong arrest in G0/G1.Cell Line:HT29 cell Concentration:100 μM Incubation Time:24 h Result:Increased the expression of p21WAF1。Cell Line:HT29 cell Concentration:100 μM Incubation Time:24 h Result:Induced p21WAF1 tanscript.
-
体内实验——
-
同义词——
-
通路Cell Cycle/DNA Damage
-
靶点HDAC
-
受体HDAC
-
研究领域——
-
适应症——
化学信息
-
CAS Number3384-24-5
-
分子量300.48
-
分子式C18H36O3
-
纯度>98% (HPLC)
-
溶解度In Vitro:?DMSO 中的溶解度 : ≥ 100 mg/mL (332.80 mM)
-
SMILESC(C(CCCCCCCCC)O)CCCCCCC(O)=O
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Calonghi N, et al. Histone deacetylase 1: a target of 9-hydroxystearic acid in the inhibition of cell growth in human colon cancer. J Lipid Res. 2005 Aug;46(8):1596-603.?
